高精度近红外脑成像系统

Correia T, Lloyd-Fox S, Everdell NL, Blasi A, Elwell C, Hebden JC, Gibson AP. Three-dimensional optical topography of brain activity in infants watching videos of human movement. Physics in Medicine and Biology 57, 1135-1146, 2012.
Cristia A., Dupoux E., Hakuna Y., Lloyd-Fox S., Schuetze M., Kivits J., Bergvelt T., van Gelder M., Filippin M., Charron S., and Minagawa-Kawai Y. An online database of infant functional Near InfraRed Spectroscopy studies: A community-augmented systematic review. PLoS One, 8, e58906, 2012.
Papademetriou, M.D., Richards, J., Correia, T., Blasi, A., Murphy, D.G., Lloyd-Fox, S., Johnson, M. & Elwell, C.E. Cortical Mapping of 3D Optical Topography in Infants. Advances in Experimental Medicine and Biology, 985, 2012.
Lloyd-Fox, S., Blasi, A., Mercure, E., Elwell, C.E. & Johnson, M.H. The emergence of cerebral specialisation for the human voice over the first months of life. Social Neuroscience, 7, 317-330, 2012.
Cooper RJ, Hebden JC, O'Reilly H, Mitra S, Mitchell A, Everdell NL, Gibson AP, Austin T. Transient haemodynamic events in neurologically compromised infants: A simultaneous EEG and diffuse optical imaging study. Neuroimage 55(4), 1610-1616, 2011.
Lloyd-Fox S, Blasi A, Everdell NL, Elwell C, Johnson MH. Selective cortical mapping of biological motion processing in young infants. Journal of Cognitive Neuroscience 23(9), 2521-2532, 2011.
Gervain, J., Mehler, J., Werker, J.F., Nelson, C.A., Csibra, G., Lloyd-Fox, S., Shukla, M. & Aslin, R.A. Near infrared spectroscopy: A report from the McDonnell Infant Methodology Consortium. Developmental Cognitive Neuroscience. 1, 22-46, 2011.
Lloyd-Fox, S., Blasi, A. & Elwell, C.E. Illuminating the developing brain: The past, present and future of functional near infrared spectroscopy. Neuroscience and Biobehavioural Reviews, 34(3), 269-284, 2010.
Blasi, A., Phillips, D., Lloyd-Fox, S., Hui-Koh, P. & Elwell, C.E. Automatic detection of motion artifacts in infant functional optical topography studies. Advances in Experimental Medicine and Biology, 662, 279-284, 2010.
Cooper RJ, Everdell NL, Enfield LC, Gibson AP, Worley A, Hebden JC. Design and evaluation of a probe for simultaneous EEG and near-infrared imaging of cortical activation. Physics in Medicine and Biology 54, 2093-2102, 2009.
Correia T, Banga A, Everdell NL, Gibson AP, Hebden JC. A quantitative assessment of the depth sensitivity of an optical topography system using a solid dynamic tissue-phantom. Physics in Medicine and Biology 54, 6277-6286, 2009.
Lloyd-Fox S, Blasi A, Volein A, Everdell NL, Elwell CE, Johnson MH. Social Perception in Infancy: a near infrared spectroscopy study. Child Development 80(4), 986-999, 2009.
Cooper RJ, Bhatt D, Everdell NL, Hebden JC. A tissue-like, optically turbid and electrically conducting phantom for simultaneous EEG and near-infrared imaging. Physics in Medicine and Biology 54, N403-N408, 2009.
Grossman, T., Johnson, M.H., Lloyd-Fox, S., Blasi, A., Deligianni, F., Elwell, C. & Csibra, G. Early cortical specialization for face-to-face communication in human infants. Proceedings of the Royal Society B, 275, 2803-2811, 2008.
Blasi A, Fox S, Everdell NL, Volein A, Tucker L, Csibra G, Gibson AP, Hebden JC, Johnson MH, Elwell CE. Investigation of depth dependent changes in cerebral haemodynamics during face perception in infants. Physics in Medicine and Biology 52, 6849-6864, 2007.
Everdell NL, Gibson AP, Tullis IDC, Vaithianathan T, Hebden JC and Delpy DT. A frequency multiplexed near-infrared topography system for imaging functional activation in the brain. Rev. Sci. Instrum. 76, 093705, 2005.

●软件：NTS数据采集软件的设计和开发基于多年在成人、儿童和婴儿中进行的fNIRS研究经验，与众多经验丰富的fNIRS研究人员一起完成。软件具有用户友好且可扩展的界面、信号优化、数据质量保证和实时反馈、灵活的事件标记、开放的数据格式等特点。

●多模态脑功能测试：NTS系统与各种神经监测、神经成像和神经设备*兼容。系统使用高质量的玻璃光纤，确保我们的技术与EEG、tDCS和TMS设备之间的干扰为零。NTS系统还旨在促进fNIRS和EEG的同时使用：系统的帽子允许EEG电极直接集成在NTS光纤上，NTS系统可以轻松地与几乎所有EEG设备同步。

功能近红外光谱成像技术（fNIRS）使用光来监测人脑功能。该技术通过将近红外光传输到头皮，然后在几厘米远的地方检测散射回头皮的光，可以测量大脑中氧合和脱氧血红蛋白浓度的变化。由于脑活动和局部血流之间存在密切的联系，血红蛋白浓度的这些变化提供了脑功能的可靠度量。NTS fNIRS系统处于这一技术增长的前沿，以易于使用和便携的方式安全地研究人脑功能。
相比其他脑功能成像技术，近红外脑功能成像技术具有良好的空间分辨率、较高的采样率、更多的测量指标、良好的舒适性和较低的成本等优点，在认知神经科学和临床研究中有着较为广泛的应用；同时由于其抗运动干扰性强、便携可穿戴等特点，系统在运动科学、脑机接口等领域的价值也逐渐被研究者所认识。具体应用案例包括驾驶员的认知负荷研究、多模态脑机接口研究、操作人的情绪状态研究等。